Effects of statins on dopamine loss and prognosis in Parkinson's disease
… total cholesterol level mediated the associations between statin use … to be associated with
cholesterol level, were entered as … statin increases striatal dopamine content without affecting …
cholesterol level, were entered as … statin increases striatal dopamine content without affecting …
Rosuvastatin improves olanzapine's effects on behavioral impairment and hippocampal, hepatic and metabolic damages in isolated reared male rats
A Mohammed, WM El-Bakly, A Ali… - Behavioural Brain …, 2020 - Elsevier
… such as serotonin (5-HT) and dopamine (DA), and dysfunction of these … In addition, statins
showed neuroprotective effects in … changes among all of the groups where: A and B, SR rats, …
showed neuroprotective effects in … changes among all of the groups where: A and B, SR rats, …
[HTML][HTML] The Potential Therapeutic Application of Simvastatin for Brain Complications and Mechanisms of Action
YM Vuu, A Kadar Shahib, M Rastegar - Pharmaceuticals, 2023 - mdpi.com
… , amongst its two groups, lipophilic statins have a higher ability … of simvastatin for 4 weeks in
Sprague–Dawley rats restored … significantly increased dopamine content in the striatum [168]…
Sprague–Dawley rats restored … significantly increased dopamine content in the striatum [168]…
[HTML][HTML] Update on statin treatment in patients with neuropsychiatric disorders
… administration of a selective serotonin reuptake-inhibitor (SSRI) [… association between
anxiety and non-adherence to statins … dopamine concentrations in the prefrontal cortex [114,115]. …
anxiety and non-adherence to statins … dopamine concentrations in the prefrontal cortex [114,115]. …
Metformin and fluoxetine improve depressive-like behavior in a murine model of Parkinsońs disease through the modulation of neuroinflammation, neurogenesis and …
IP Mendonça, IHR de Paiva, EP Duarte-Silva… - International …, 2022 - Elsevier
… IL-1β in the prefrontal cortex and iNOS levels in the hippocampus. Both … between
cholinergic and dopaminergic activity in the … reuptake inhibitors (SSRIs) and also has anti-inflammatory …
cholinergic and dopaminergic activity in the … reuptake inhibitors (SSRIs) and also has anti-inflammatory …
The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies
… For statins or omega-3 fatty acids similar results were … IL-6 levels in the prefrontal cortex,
hypothalamus, striatum, and … link among inflammation, depression, and monoamine reuptake …
hypothalamus, striatum, and … link among inflammation, depression, and monoamine reuptake …
Repeated ethanol exposure influences key enzymes in cholesterol and lipid homeostasis via the AMPK pathway in the rat prefrontal cortex
… study examined the dose- and time-response effects of acute … times per week from Monday
to Friday between 10:00 and 16:… to dopamine D 2 receptors, the dopamine reuptake inhibitor, …
to Friday between 10:00 and 16:… to dopamine D 2 receptors, the dopamine reuptake inhibitor, …
Hyperactivation of the amygdala correlates with impaired social play behavior of prepubertal male rats in a maternal immune activation model
… between neutral odors and their nest odor, moderate effect in … cells in the prefrontal cortex
and striatum, but hyperactivation … of dopamine and norepinephrine reuptake transporters, is a …
and striatum, but hyperactivation … of dopamine and norepinephrine reuptake transporters, is a …
[HTML][HTML] Immune targets for therapeutic development in depression: towards precision medicine
WC Drevets, GM Wittenberg, ET Bullmore… - Nature reviews Drug …, 2022 - nature.com
… , especially to selective serotonin reuptake inhibitors (SSRIs) … For example, statins, in addition
to their lipid-lowering effects, … connectivity between ventro-medial prefrontal cortex (vmPFC…
to their lipid-lowering effects, … connectivity between ventro-medial prefrontal cortex (vmPFC…
Saffron extract-induced improvement of depressive-like behavior in mice is associated with modulation of monoaminergic neurotransmission
C Monchaux De Oliveira, L Pourtau, S Vancassel… - Nutrients, 2021 - mdpi.com
… to hemilaterally collect the frontal cortex (FCx), striatum (Str) … study therefore suggests that,
among the different bioactive … of basal 5-HT levels, but they did reduce SERT reuptake activity, …
among the different bioactive … of basal 5-HT levels, but they did reduce SERT reuptake activity, …